Resolution:
## Figure 2.
Comparison of Likelihood Assumptions in EMIM. Results from simulated data. (A-C) The power of likelihood ratio tests to achieve significance levels (p-values) of
0.001, 0.01 and 0.05 for different simulated effects and likelihood assumptions: HWE
- Hardy-Weinberg Equilibrium; CEPG - Conditional on Exchangeable Parental Genotypes;
CPG - Conditional on Parental Genotypes; PAE - Parental Allelic Exchangeability. (D-F) Box plots on a log-scale of parameter estimates for R_{1}, R_{2}, S_{1}, S_{2}and I_{m}, assuming HWE. Dotted lines show the true parameter values.
Howey and Cordell |