Open Access Methodology article

Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures

Andrew F Neuwald1*, Christopher J Lanczycki2 and Aron Marchler-Bauer2

Author Affiliations

1 Institute for Genome Sciences and Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, BioPark II, Room 617, 801 West Baltimore St, Baltimore, MD 21201, USA

2 National Center for Biotechnology Information; National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA

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BMC Bioinformatics 2012, 13:144  doi:10.1186/1471-2105-13-144

Published: 22 June 2012

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Additional figures referred to in the main article as Figures S1–S6.

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