Table 7 |
||
False positive rates when null hypothesis is simulated by generating random expression data | ||
α=0.05 | α=0.01 | |
PADOG | 0.051 | 0.012 |
GSA | 0.052 | 0.015 |
GSEA | 0.052 | 0.012 |
^{}The fraction of all pathways significant at α=0.05 and α=0.01 were computed after applying the three analysis methods on 1200 datasets having expression data generated from a random normal N(0,1) distribution. The collection of gene sets used in the analysis was defined by the 229 KEGG non-metabolic and metabolic pathways.
Tarca et al.
Tarca et al. BMC Bioinformatics 2012 13:136 doi:10.1186/1471-2105-13-136