Table 9

The top 5 enriched GO terms for each dysregulated pathway in pancreatic tumour (GSE16515) dataset
Pathway GO: term p-value Term name
KEGG_P53_SIGNALING_PATHWAY GO:0051726 1.30E-33 regulation of cell cycle
GO:0006917 1.30E-22 induction of apoptosis
GO:0012502 1.50E-22 induction of programmed cell death
GO:0006915 1.10E-20 apoptosis
GO:0042981 1.20E-20 regulation of apoptosis
ST_JNK_MAPK_PATHWAY GO:0000165 6.70E-33 MAPKKK cascade
GO:0023014 8.90E-27 signal transmission via phosphorylation event
GO:0007243 8.90E-27 intracellular protein kinase cascade
GO:0031098 1.40E-23 stress-activated protein kinase signaling cascade
GO:0007254 8.60E-22 JNK cascade
ST_P38_MAPK_PATHWAY GO:0044087 1.40E-13 regulation of cellular component biogenesis
GO:0043254 4.70E-13 regulation of protein complex assembly
GO:0030833 3.30E-12 regulation of actin filament polymerization
GO:0030036 4.40E-12 actin cytoskeleton organization
GO:0008064 6.40E-12 regulation of actin polymerization or depolymerization
BIOCARTA_SALMONELLA_PATHWAY GO:0006793 1.70E-17 phosphorus metabolic process
GO:0006796 1.70E-17 phosphate metabolic process
GO:0006468 4.10E-17 protein amino acid phosphorylation
GO:0016310 1.30E-16 phosphorylation
GO:0043687 9.20E-16 post-translational protein modification
BIOCARTA_CDC42RAC_PATHWAY GO:0044087 1.20E-14 regulation of cellular component biogenesis
GO:0043254 3.10E-12 regulation of protein complex assembly
GO:0032956 3.30E-12 regulation of actin cytoskeleton organization
GO:0032970 4.20E-12 regulation of actin filament-based process
GO:0030833 1.50E-11 regulation of actin filament polymerization

Liu et al.

Liu et al. BMC Bioinformatics 2012 13:126   doi:10.1186/1471-2105-13-126

Open Data