Table 3

Dysregulated pathways identified in lung cancer (GSE4115) dataset
Pathway Description Number of genes
REACTOME_SPHINGOLIPID_METABOLISM Genes involved in sphingolipid metabolism 32
REACTOME_TRIACYLGLYCERIDE_BIOSYNTHESIS Genes involved in triacylglyceride biosynthesis 14
REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol 14
REACTOME_TCR_SIGNALING Genes involved in TCR signaling 64
BIOCARTA_STATHMIN_PATHWAY Stathmin and breast cancer resistance to antimicrotubule agents 19
ST_T_CELL_SIGNAL_TRANSDUCTION T Cell signal transduction 44
BIOCARTA_SPRY_PATHWAY Sprouty regulation of tyrosine kinase signals 18
ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway 7
BIOCARTA_INTEGRIN_PATHWAY Integrin signaling pathway 38
BIOCARTA_CELL2CELL_PATHWAY Cell to cell adhesion signaling 14
REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in apoptotic cleavage of cell adhesion proteins 11

Liu et al.

Liu et al. BMC Bioinformatics 2012 13:126   doi:10.1186/1471-2105-13-126

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