Table 3

Top ten modules with significant biological enrichment in KEGG

Cluster ID

KEGG Pathway

Total number of proteins in the module

Number of proteins in the KEGG Pathway from the module

Total number of proteins in the KEGG Pathway

Fisher’s p-value


1

RNA polymerase / Transcription / Genetic Information Processing

10

10

29

5.10E-24

2

Progesterone-mediated oocyte maturation / Endocrine System / Cellular Processes

12

12

86

1.91E-22

3

Proteasome / Folding_ Sorting and Degradation / Genetic Information Processing

17

12

48

5.22E-22

4

Basal transcription factors / Transcription / Genetic Information Processing

9

9

36

1.24E-20

5

Cell cycle / Cell Growth and Death / Cellular Processes

12

12

128

2.97E-20

6

Ubiquitin mediated proteolysis / Folding_ Sorting and Degradation / Genetic Information Processing

12

12

138

7.61E-20

7

Cell cycle / Cell Growth and Death / Cellular Processes

13

12

128

3.78E-19

8

Pyrimidine metabolism / Nucleotide Metabolism / Metabolism

10

10

98

3.57E-18

9

Oocyte meiosis / Cell Growth and Death / Cellular Processes

12

11

114

4.09E-18

10

RNA degradation / Folding_ Sorting and Degradation / Genetic Information Processing

11

9

59

8.97E-17


*the highest level to the lowest level of KEGG pathways (maptitle / subcategory / category) are show

Martha et al. BMC Bioinformatics 2011 12(Suppl 10):S7   doi:10.1186/1471-2105-12-S10-S7

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