Coherence of a gene expression module. The genes in the previously-described CIN70 signature are consistently correlated in multiple data sets and measurement platforms. For the 23 CIN70 genes that are queried by more than one probe set, we identified the highest-scoring probe set (HSPS) and the lowest-scoring probe set (LSPS), and calculated the Pearson correlation coefficient (r) between each of these probe sets and the median of all CIN70 genes. The HSPS and LSPS were identified by either a) overall score, b) sensitivity score, or c) robustness score.
Li et al. BMC Bioinformatics 2011 12:474 doi:10.1186/1471-2105-12-474