Table 3

Five most significant genes identified by CDEP as related to common metastatic mechanism across different cancer types by using FDR < 0.05 as threshold

Up-regulated genes

Down-regulated genes


Glycoprotein (transmembrane) nmb (GPNMB)

Serpin peptidase inhibitor, clade B (ovalbumin), member 5 (SERPINB5)

Secreted phosphoprotein 1 (SPP1)

proteasome (prosome, macropain) subunit, beta type, 9 (PSMB9)

Transforming growth factor, beta-induced (TGFBI)

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (MX1)

Heat shock 27kDa protein 1 (HSPB1)

interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)

Mesoderm specific transcript homolog (MEST)

ubiquitin D (UBD)


Tsoi et al. BMC Bioinformatics 2011 12:438   doi:10.1186/1471-2105-12-438

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