Comparison of the average stationary behavior of the CPME model that incorporates deterministic reaction dynamics with the steady state of the structured continuum model. [Iex] = 24 μM for all simulations and all other parameters as in Table 3. Panel (a): Predictions from the cell population model agree with those from the structured continuum model when the average values for A/V and [O]T are used. For the solid S-shaped curve, the average values for A/V and [O]T were taken from the population simulations. For the dashed curve, the average values were estimated using Eqs. 8 and 9. Panel (b): a representative bimodal NDF and the corresponding averages and standard deviation.
Stamatakis and Zygourakis BMC Bioinformatics 2011 12:301 doi:10.1186/1471-2105-12-301