Table 3

List of the 39 genes with both promoter and distal ETS1 peaks.

# Gene ID Gene Description


AKAP11 A-kinase anchor protein 11 2

AKR1A1 alcohol dehydrogenase 3

ATP5O ATP synthase subunit O, mitochondrial precursor 4

C1orf109 hypothetical protein LOC54955 5

C2orf29 hypothetical protein LOC55571 6

C9orf123 transmembrane protein C9orf123 7

CDK9 cell division protein kinase 9 8

CHSY1 chondroitin sulfate synthase 1 9

CKAP2L cytoskeleton-associated protein 2-like 10

CLINT1 clathrin interactor 1 11

DUSP2 dual specificity protein phosphatase 2 12

DUSP6 dual specificity protein phosphatase 6 isoform 13

HSPC157 hypothetical LOC29092 14

KIAA0427 CBP80/20-dependent translation initiation factor 15

LDHA L-lactate dehydrogenase A chain isoform 5 16

LOC100188949 hypothetical LOC100188949 17

LOC285456 hypothetical LOC285456 18

LSM14B protein LSM14 homolog B 19

MAX protein max isoform a 20

MRPS18A 28S ribosomal protein S18a, mitochondrial 21

MTF2 metal-response element-binding transcription 22

NAIF1 nuclear apoptosis-inducing factor 1 23

NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha 24

POMP proteasome maturation protein 25

PSMA6 proteasome subunit alpha type-6 26

RBM16 putative RNA-binding protein 16 27

RBM38 RNA-binding protein 38 isoform a 28

RPN1 dolichyl-diphosphooligosaccharide--protein 29

SEPHS2 selenide, water dikinase 2 30

SIRPG signal-regulatory protein gamma isoform 1 31

SPRED2 sprouty-related, EVH1 domain-containing protein 32

TFRC transferrin receptor protein 1 33

TMEM18 transmembrane protein 18 34

TRIP13 thyroid receptor-interacting protein 13 isoform 35

TXN2 thioredoxin, mitochondrial precursor 36

UBE2D2 ubiquitin-conjugating enzyme E2 D2 isoform 1 37

ZFAT zinc finger protein ZFAT isoform 1 38

ZNF212 zinc finger protein 212 39

ZNF683 zinc finger protein 683


The table shows the 39 genes that were found to have both promoter and intergenic ETS1 peaks. It is possible that ETS1 binding at the promoters and enhancers of these genes is explained by looping of the distal elements onto proximal promoters. This hypothesis could be tested using chromosome conformation capture based techniques.

Giannopoulou and Elemento BMC Bioinformatics 2011 12:277   doi:10.1186/1471-2105-12-277

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