Table 5

Three novel missense somatic mutations of DNMT3A identified in 23 samples using seqgene (cov > 10)

transcript

position (hg19)

position

transcript

codon number

amino acid change

ref

bl3

bm3

bl9

bm9

ex5


NM_022552

chr2:25457197

2947

897

Val- > Asp

A

A

A/T


NM_175629

chr2:25457197

3028

897

Val- > Asp

A

A

A/T


NM_153759

chr2:25457197

2237

708

Val- > Asp

A

A

A/T


NM_022552

chr2:25467449

1884

543

Gly- > Cys

C

A/C


NM_175629

chr2:25467449

1965

543

Gly- > Cys

C

A/C


NM_153759

chr2:25467449

1174

354

Gly- > Cys

C

A/C


NM_022552

chr2:25457242

2902

882

Arg- > His

C

C/T

C


NM_175629

chr2:25457242

2983

882

Arg- > His

C

C/T

C


NM_153759

chr2:25457242

2192

693

Arg- > His

C

C/T

C


Deng BMC Bioinformatics 2011 12:267   doi:10.1186/1471-2105-12-267

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