Additional file 1.
Boxplot of estimated MAFs using ML methods with known or unknown minor allele. Boxplot of estimated MAFs of SNPs corresponding to each sample allele frequency. Assuming 1,000 individuals, 1,000 SNPs with true MAF of 0.5% were simulated at individual sequencing depth of 8X. For each SNP, sample allele frequency was obtained using true genotypes (x-axis). Then each boxplot was drawn using estimated MAFs with known (left) and unknown(right) minor alleles.
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Kim et al. BMC Bioinformatics 2011 12:231 doi:10.1186/1471-2105-12-231