Resolution:
## Figure 5.
Receiver operating characteristic (ROC) curves of four tests of association. For the definition of the four statistics, see the caption of Figure 4. Assuming
500 cases and 500 controls, a set of 20,000 sites were simulated under the null and
under the alternative at individual sequencing depths of 2×, 5×, and 10× (three columns).
At each false positive rate (x-axis), the corresponding critical value was computed
using the empirical null distribution. The true positive rate (power; y-axis) was
obtained by computing the fraction of causative sites with test statistics that exceed
the critical value.
Kim |