Table 10

Top ranking co-occurring domains in novel yeast interactions.

Domain Name A

Domain Name B

DOMINE

Number of sites


Actin-like

Retrotransposon Ty1 A, N-terminal

Known

360

Serine/threonine-protein kinase-like domain

Serine/threonine-protein kinase-like domain

Known

221

Protein kinase-like domain

Serine/threonine-protein kinase-like domain

Novel

170

Sugar/inositol transporter

Protein kinase-like domain

Novel

106

Ras GTPase

Serine/threonine-protein kinase-like domain

Known

99

Ras GTPase

Ras GTPase

Known

95

Ras GTPase

Small GTPase, Rho type

Known

57

ATPase, AAA-type, core

ATPase, AAA-type, core

Known

56

ATPase, AAA-type, core

ATPase, AAA-type, conserved site

Novel

52

Sugar/inositol transporter

Serine/threonine-protein kinase-like domain

Known

51


Out of the 100 most frequently occurring domain pairs, 55% are reported in the DOMINE database.

Amos-Binks et al. BMC Bioinformatics 2011 12:225   doi:10.1186/1471-2105-12-225

Open Data