Multi-species interolog distribution. Interologs from different species are clustered in different colours. Three kinds of data are counted: A. integrated protein interaction, B. ortholog protein groups and C. predicted rice protein interactions. Homo sapiens contributes most protein interactions in our integrated protein-protein interaction database, and Arabidopsis thaliana contributes most in InParanoid orthologous protein groups, which shares the highest evolutionary conservation with rice. Nearly 74% of our final predictions are from Saccharomyces cerevisiae, which has the highest coverage of its whole genome.
Gu et al. BMC Bioinformatics 2011 12:161 doi:10.1186/1471-2105-12-161