Area under the ROC curve is increased by removing a poor quality array. ROC curves for detection of the 16 spiked-in transcripts using all 8 arrays (black line) and with each array removed (gray lines). The red ROC curve corresponds to removing array 4. Removing array 4 results in the largest increase in the area under the ROC curve suggesting that array 4 may be of poor quality.
McCall et al. BMC Bioinformatics 2011 12:137 doi:10.1186/1471-2105-12-137