Table 1

Summary of the data contained in the EDKB database

Assay type

Number of records

Standard chemical to be compared

Endpoint

Log (Activity) Range


Estrogen Receptor Binding

616

Estradiol (2.0)

*RBA

From 2.94 to -4.5

Androgen Receptor Binding

230

R1881 (2.0)

RBA

From 3.18 to -3.56

Uterotropic

1707

Estradiol (2.0)

**RP

From 3.93 to -3.44

Cell proliferation

160

Estradiol (2.0)

***RPP

From 3.0 to -4.22

Reporter gene

544

Estradiol (2.0)

RP

From 2.18 to -5.38


A summary of the distribution of data, standard chemicals to be compared, endpoints, and activity ranges.

The values in parentheses are log activity for a standard chemical

* RBA: Relative Binding Affinity

** RP: Relative Potency

*** RPP: Relative Proliferation Potency

Ding et al. BMC Bioinformatics 2010 11(Suppl 6):S5   doi:10.1186/1471-2105-11-S6-S5

Open Data