Table 1

Definition of true and false positive rates. Synopsis of the rules for calling true/false positives and negatives, which take into account the sign of the direction of differential expression: "+" for over-expression in UHR, "-" for over-expression in Brain.

mRNA-Seq

Non-DE

DE +

DE-


Non-DE

TN

FP

FP

N

qRT-PCR

DE +

FN

TP

FP

P

DE-

FN

FP

TP


The true positive rate (TPR) is estimated as TP/P and the false positive rate (FPR) as FP/N.

Bullard et al. BMC Bioinformatics 2010 11:94   doi:10.1186/1471-2105-11-94

Open Data