System architecture of the L2N software. The system contains several related components (blue ellipses). Registered users are able to upload lists of genes/proteins. Set operations allow users to create new lists from existing lists. Overlap analyses use background databases of gene-list libraries to compute enrichment. Lists of genes are able to be expanded using background knowledge networks of PPIs, co-expression, and co-annotations. Users have the capability to share their lists with other users and communicate with other users through a messaging system.
Lachmann and Ma'ayan BMC Bioinformatics 2010 11:87 doi:10.1186/1471-2105-11-87