Methodology article

Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing

Corey M Yanofsky¹ and David R Bickel^1,²^*

¹ Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada

² Department of Mathematics and Statistics, University of Ottawa, Ottawa, Canada

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BMC Bioinformatics 2010, 11:63 doi:10.1186/1471-2105-11-63

Published: 28 January 2010

Additional file 1:

This file contains a heuristic overview and detailed derivation of our Bayes factor approach to calculating probabilities of differential expression.

Format: DOCX Size: 49KB Download file