Table 6

Co-localization scores for predicted components from MCL and MCL-CAw

Co-localization scores

PPI Network

MCL clusters

MCL-CAw cores

MCL-CAw complexes


Gavin+Krogan

0.730

0.890

0.866

ICD(Gavin+Krogan)

0.830

0.936

0.912

FSW(Gavin+Krogan)

0.830

0.931

0.912

Consolidated3.19

0.790

0.923

0.908

Bootstrap0.094

0.788

0.895

0.874


Findings: (i) The complexes produced after CA-refinement showed higher scores than those of MCL; (ii) The complexes predicted from the scored networks showed higher scores than from the Gavin+Krogan network; (iii) The cores in MCL-CAw showed higher scores than whole complexes.

Srihari et al. BMC Bioinformatics 2010 11:504   doi:10.1186/1471-2105-11-504

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