ChIP-chip to point process. Illustration of the way in which data from the ChIP-chip experiment can be viewed as a point process. In each cell, the different TREs are positioned along the double stranded DNA-sequence (top). The abundance of binding sites across cells at a particular position of the sequence results in a signal generated from the ChIP-chip experiment (middle). The midpoint of the interval where the signal is above a specified cut off is used as a proxy for the actual binding site. The midpoints for each of the TREs considered are viewed as points from a multivariate point process along the line (bottom).
Carstensen et al. BMC Bioinformatics 2010 11:456 doi:10.1186/1471-2105-11-456