Phylogenies inferred on components derived from Jones et al. . Each phylogeny shows nodes labeled with component numbers. We further manually added labels reflecting approximately which tumor types are most specifically labeled by a given component based on Tables 1 and 2: NOR (normal cells); LCC/AD (large cell carcinoma and adenocarcinoma); SCC (small cell); CA (carcinoid); CMB (combined small cell/adenocarcinoma) and NOR/SCC (normal and small cell). Edges with over 50% confidence are shown as solid lines while those between 10% and 50% confidence are shown as dashed lines. Edges with confidence below 10% are omitted. Edges are labeled by confidences rounded to the nearest percent. (a) Phylogeny derived from four mixture components. (b) Phylogeny derived from six mixture components.
Schwartz and Shackney BMC Bioinformatics 2010 11:42 doi:10.1186/1471-2105-11-42