Comparative clustering of the telomere dataset. (a-c) Proper identification of overlapping populations. Although two populations shown by red and blue contours are overlapping in all bi-variant plots of this 3-dimensional sample, SamSPECTRAL can properly distinguish them by considering multiple parameters simultaneously.(d) SamSPECTRAL can also identify two major subpopulations of granulocytes correctly, as verified by expert analysis. (e) flowMerge does not distinguish between two populations of interest, and (f) FLAME improperly splits the same sample into several clusters.
Zare et al. BMC Bioinformatics 2010 11:403 doi:10.1186/1471-2105-11-403