BMC Bioinformatics

official impact factor 3.03

Open Access Research article

Predicting Bevirimat resistance of HIV-1 from genotype

Dominik Heider1*, Jens Verheyen2 and Daniel Hoffmann1

Author Affiliations

1 Department of Bioinformatics, Center of Medical Biotechnology, University of Duisburg-Essen, Universitaetsstr. 2, 45117 Essen, Germany

2 Institute of Virology, University of Cologne, Fuerst-Pueckler-Str. 56, 50935 Cologne, Germany

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BMC Bioinformatics 2010, 11:37 doi:10.1186/1471-2105-11-37

Published: 20 January 2010

Additional files

Additional file 1:

Data set. The sequences used in this study.

Format: XLS Size: 160KB Download file

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Additional file 2:

MSA of the sequences with clustalw. Multiple sequence alignment of the sequences with clustalw [23].

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Additional file 3:

MSA of the sequences with t-coffee. Multiple sequence alignment of the sequences with t-coffee [24].

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Additional file 4:

Plots and rules. Variance plots and prediction rules.

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Additional file 5:

Cleavage site predictions. Predictions are made with HIVcleave [31].

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Additional file 6:

Shifted cleavage site probabilities. Probable HIV-protease cleavage sites are shown in bold [31]. The value represents the probability of protease cleavage.

Format: XLS Size: 105KB Download file

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Additional file 7:

Secondary structure predictions. Predictions are made with JPred [43].

Format: XLS Size: 309KB Download file

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