Figure 7.

Graphical representation of the SPARQL query for Case Study 2. PubChem compounds (e.g. CID 573747) are identified that are active in bioassays that are associated with protein targets, which are associated with genes (via UNIPROT) which are identified as being part of the MAPK signalling pathway (via KEGG). We thus identify compounds which have multiple paths, and thus which interact with multiple targets in this protein.

Chen et al. BMC Bioinformatics 2010 11:255   doi:10.1186/1471-2105-11-255
Download authors' original image