Graphical representation of the SPARQL query for Case Study 1. PubChem compounds (e.g. CID 5754) are identified that are active in bioassays that are associated with protein targets, which are associated with genes (via UNIPROT), which are identified as those with which Dexamethasone interacts (via DrugBank). The resultant compounds are thus those that have a similar activity profile to Dexamethasone.
Chen et al. BMC Bioinformatics 2010 11:255 doi:10.1186/1471-2105-11-255