BMC Bioinformatics

official impact factor 3.03

Open Access Methodology article

TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

Henrik Bengtsson1*, Pierre Neuvial1 and Terence P Speed1,2

Author Affiliations

1 Department of Statistics, University of California, Berkeley, USA

2 Bioinformatics Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia

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BMC Bioinformatics 2010, 11:245 doi:10.1186/1471-2105-11-245

Published: 12 May 2010

Additional files

Additional file 1:

Affymetrix GenomeWideSNP_6 data after CRMAv2 preprocessing (sample TCGA-23-1027). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the CRMAv2 method.

Format: PDF Size: 1.3MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

Affymetrix GenomeWideSNP_6 data after CRMAv2 preprocessing (sample TCGA-23-1027; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the CRMAv2 method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 1.3MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

Affymetrix GenomeWideSNP_6 data after ismpolish preprocessing (sample TCGA-23-1027). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the ismpolish method.

Format: PDF Size: 1.2MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 4:

Affymetrix GenomeWideSNP_6 data after ismpolish preprocessing (sample TCGA-23-1027; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the ismpolish method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 1.2MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 5:

Illumina Human1M-Duo data after BeadStudio,XY preprocessing (sample TCGA-23-1027). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Illumina Human1M-Duo data set preprocessed with the BeadStudio,XY method.

Format: PDF Size: 851KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 6:

Illumina Human1M-Duo data after BeadStudio,XY preprocessing (sample TCGA-23-1027; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Illumina Human1M-Duo data set preprocessed with the BeadStudio,XY method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 849KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 7:

Illumina Human1M-Duo data after BeadStudio,BAF preprocessing (sample TCGA-23-1027). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Illumina Human1M-Duo data set preprocessed with the BeadStudio,BAF method.

Format: PDF Size: 819KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 8:

Illumina Human1M-Duo data after BeadStudio,BAF preprocessing (sample TCGA-23-1027; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-23-1027 in the Illumina Human1M-Duo data set preprocessed with the BeadStudio,BAF method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 818KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 9:

Affymetrix GenomeWideSNP_6 data after CRMAv2 preprocessing (sample TCGA-02-0001). Assessment of TumorBoost based on tumor/normal pair TCGA-02-0001 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the CRMAv2 method.

Format: PDF Size: 1.7MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 10:

Affymetrix GenomeWideSNP_6 data after CRMAv2 preprocessing (sample TCGA-02-0001; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-02-0001 in the Affymetrix GenomeWideSNP_6 data set preprocessed with the CRMAv2 method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 1.7MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 11:

Illumina HumanHap550 data after BeadStudio,XY preprocessing (sample TCGA-02-0001). Assessment of TumorBoost based on tumor/normal pair TCGA-02-0001 in the Illumina HumanHap550 data set preprocessed with the BeadStudio,XY method.

Format: PDF Size: 1.5MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 12:

Illumina HumanHap550 data after BeadStudio,XY preprocessing (sample TCGA-02-0001; with confidence scores). Assessment of TumorBoost based on tumor/normal pair TCGA-02-0001 in the Illumina HumanHap550 data set preprocessed with the BeadStudio,XY method using the SNPs with 90% highest confidence scores.

Format: PDF Size: 1.5MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data