Figure 5.

The identified Notch pathway including several growth factors, transcription factors and oncogenes. Some of the members (e.g., NOTCH3, JAG1, JAG2 and SOX2) are known to be associated with the Notch pathway while several novel members are revealed by the COCA approach, e.g., transcription factors: TCF4, TBP and PITX2; oncogenes: MYCN, FGFR1 and CCND1.

Wang et al. BMC Bioinformatics 2010 11:162   doi:10.1186/1471-2105-11-162
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