Flowchart describing the individual steps of an ABC estimation by ABCtoolbox. Black arrows indicate the standard approach. Some alternative paths are shown with dotted lines. For instance, it is possible to modify the output of a simulation program such as to allow one to take specific characteristics of the observed data into account such as a given level of missing data. Additionally, ABCtoolbox can call several simulation programs per iteration, each of which can be launched with the same parameter values. Thus, different data types can be conveniently combined in a single analysis.
Wegmann et al. BMC Bioinformatics 2010 11:116 doi:10.1186/1471-2105-11-116