Squamous cell carcinoma tumor and perilesional display distinctly different scatter plots from normal tissue. Representative scatter plots of average normal versus perilesional (A) and cancer (B) samples from patient 1, for gene subset 1. R is depicted by the dashed line around the normal baseline line (slope = 1). The value for R is optimized for differentiation between groups for each subset of genes.
Botting et al. BMC Bioinformatics 2009 10:66 doi:10.1186/1471-2105-10-66