Resolution:
## Figure 8.
Standard and effective affinity range for different transcription factors. (a) Estimation of the affinity range for the different transcription factors analyzed
in this work. For each transcription factor, the affinity range is represented as
the distribution of affinities for all its experimentally determined binding sites.
The affinity of each binding site is estimated using the R_{sequence }· BvH ranking index. (b) Estimation of the effective affinity range. For each transcription
factor, the effective affinity range is represented as the distribution of normalized
affinities for all its experimentally determined binding sites. Normalized affinities
are estimated by normalizing the R_{sequence }· BvH ranking index for each site with the number of false positives required to find
that site. For comparison purposes, in both affinity range plots R_{sequence }· BvH values (Y-axis) are normalized to the length of the binding motif for each transcription
factor and ranges (X-axis) are shown as the percentage of experimentally determined
sites (collection).
Erill and O'Neill |