Speedup of BLASTX searches for differently sized queries with and without query splitting. Different sized pieces of [Genbank:NC_007113.2] were searched against a set of human proteins. The query length in kbases is on the x-axis, with a log scale. On the y-axis is the fractional speedup, which is defined as (Tbaseline/Tblastx) - 1. Three searches were performed with both the baseline and the blastx applications (for each data point), and the lowest time for each application was used.
Camacho et al. BMC Bioinformatics 2009 10:421 doi:10.1186/1471-2105-10-421