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Open Access Highly Accessed Research article

Ensemble approach to predict specificity determinants: benchmarking and validation

Saikat Chakrabarti and Anna R Panchenko

Author Affiliations

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA

BMC Bioinformatics 2009, 10:207  doi:10.1186/1471-2105-10-207

Published: 2 July 2009

Additional files

Additional file 1:

Ensemble approach to predict specificity determinants: benchmarking and validation. Table listing prediction sensitivities of different methods.

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Additional file 2:

Ensemble approach to predict specificity determinants: benchmarking and validation. Precision-Recall (PR) curves.

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Additional file 3:

Ensemble approach to predict specificity determinants: benchmarking and validation. List of potential subsites identified in validation dataset.

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Additional file 4:

Ensemble approach to predict specificity determinants: benchmarking and validation. Comparison of performance of different methods.

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Additional file 5:

Ensemble approach to predict specificity determinants: benchmarking and validation. Prediction dataset.

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Additional file 6:

Ensemble approach to predict specificity determinants: benchmarking and validation. List of potential subsites predicted in prediction dataset.

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Additional file 7:

Ensemble approach to predict specificity determinants: benchmarking and validation. Spatial distances among the predicted C3 and C2 sites for six families within the prediction dataset.

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Additional file 8:

Ensemble approach to predict specificity determinants: benchmarking and validation. Structural property analysis of potential (C3 and C2 sites) subsites within the prediction dataset.

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Additional file 9:

Ensemble approach to predict specificity determinants: benchmarking and validation. Validation dataset.

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Additional file 10:

Ensemble approach to predict specificity determinants: benchmarking and validation. List of actual subsites.

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Additional file 11:

Ensemble approach to predict specificity determinants: benchmarking and validation. Additional information about validation dataset.

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