Evolution as a function of the iterations. From left to right, the original HIV-1 tomogram and the results with TOMOBFLOW at 10, 25, 50, 100 and 150 iterations are shown. The background is progressively flattened with the iterations whereas the structural features remain sharp. At high number of iterations, some edges begin to look blurred.
Fernandez BMC Bioinformatics 2009 10:178 doi:10.1186/1471-2105-10-178