BMC Bioinformatics

official impact factor 3.03

Open Access Software

Automated FingerPrint Background removal: FPB

Simone Scalabrin1,2*, Michele Morgante1,3 and Alberto Policriti1,2

Author Affiliations

1 Istituto di Genomica Applicata (IGA), via J. Linussio 51, I-33100 Udine, Italy

2 Department of Mathematics and Computer Science, University of Udine, via delle Scienze 206, I-33100 Udine, Italy

3 Department of Agriculture and Environmental Sciences, University of Udine, via delle Scienze 208, I-33100 Udine, Italy

For all author emails, please log on.

BMC Bioinformatics 2009, 10:127 doi:10.1186/1471-2105-10-127

Published: 30 April 2009

Additional files

Additional file 1:

Particular cases of peaks to be removed. Partially digested fragments, star activity by-products, "machine" background, and E. coli peaks present particular features and need to be removed accordingly.

Format: PDF Size: 193KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

Distribution of true peaks vs background peaks. True and background peaks distribute differently from clone to clone and from dye to dye. Therefore, different scenarios may arise and particular care in background removal should be used.

Format: PDF Size: 108KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data