Table 5

Profile support

Profile

# CGIs (%)

Methylation pattern


1

84 (16.25)

Constitutively methylation

2

50 (8.51)

Unmethylated in sperm

3

36 (6.69)

Differentially methylated

4

68 (13.15)

Constitutively unmethylated

5

36 (6.96)

6

62 (11.99)

7

76 (14.70)

8

60 (11.60)

9

29 (5.61)


Misclassified

22 (4.26)


A CGI was defined as being misclassified if it lacked an experimental methylation value in sperm but was classified nonetheless as constitutively methylated or unmethylated solely in sperm. CGIs that were missing methylation data in more than half of tissues and cell types under analysis were also defined as misclassified and removed.

Previti et al. BMC Bioinformatics 2009 10:116   doi:10.1186/1471-2105-10-116

Open Data