Table 3

CGI profiles: Methylation values of each non-redundant CGI profile.

Constitutively methylated

Unmethylated in sperm

Differentially methylated

Constitutively unmethylated


Tissue/Cell type

1

2

3

4

5

6

7

8

9


CD4

0.916

0.881

0.655

0.074

0.078

0.065

0.076

0.094

0.072

CD8

0.912

0.905

0.683

0.089

0.078

0.071

0.104

0.136

0.092

DF

0.876

0.758

0.595

0.070

0.066

0.068

0.079

0.082

0.045

DK

0.866

0.708

0.531

0.077

0.061

0.063

0.072

0.074

0.086

DM

0.900

0.854

0.734

0.093

0.103

0.079

0.102

0.133

0.108

FL

0.842

0.762

0.562

0.104

0.117

0.105

0.138

0.158

0.157

FSM

0.842

0.793

0.619

0.097

0.136

0.127

0.125

0.118

0.052

HM

0.913

0.867

0.688

0.068

0.071

0.059

0.064

0.072

0.059

Liver

0.900

0.883

0.691

0.073

0.071

0.065

0.080

0.095

0.077

Placenta

0.878

0.846

0.679

0.085

0.075

0.066

0.096

0.098

0.123

SM

0.866

0.804

0.558

0.071

0.072

0.057

0.062

0.078

0.067

Sperm

0.836

0.178

0.359

0.102

0.086

0.105

0.125

0.117

0.112


Average methylation ± Std

0.879 ± 0.065

0.770 ± 0.1

0.613 ± 0.202

0.084 ± 0.066

0.085 ± 0.068

0.078 ± 0.058

0.094 ± 0.074

0.105 ± 0.088

0.088 ± 0.065


Average and tissue-specific methylation values of the nine non-redundant CGI profiles. The methylation values mentioned during the comparison of the profiles are marked in bold and all differences between profiles are supported by a MWW p-value lower than 0.01.

Previti et al. BMC Bioinformatics 2009 10:116   doi:10.1186/1471-2105-10-116

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