BMC Bioinformatics

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Open Access Highly Access Methodology article

EFICAz2: enzyme function inference by a combined approach enhanced by machine learning

Adrian K Arakaki1, Ying Huang2 and Jeffrey Skolnick1*

Author Affiliations

1 Center for the Study of Systems Biology, School of Biology, Georgia Institute of Technology, Atlanta, Georgia, 30318, USA

2 California Institute for Telecommunications and Information Technology, University of California, San Diego, La Jolla, CA, 92093, USA

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BMC Bioinformatics 2009, 10:107 doi:10.1186/1471-2105-10-107

Published: 13 April 2009

Additional files

Additional file 1:

Figure S1. Example of Functionally Discriminating Residues (FDRs).

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Additional file 2:

Novel enzyme function annotations of the human proteome by EFICAz2. Excel spreadsheet listing all the three-field or four-field EC numbers assigned by EFICAz2 version 13 to human proteins that were not annotated as enzymes in the Release 47.0 of the KEGG database.

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Open Data