Table 2

Amino acids selected in a peptide library screen for Dbf2-Mob1 substrates

-7

-6

-5

-4

-3

-2

-1

0

+1

+2

+3

+4


X

X

X

M(1.4)

R

I(2.8)

F(2.8)

S

M(1.4)

X

X

X

F(1.1)

V(1.7)

V(1.6)

I(1.1)

H(1.7)

I(1.3)

L(1.1)

M(1.2)

M(1.1)

V(1.1)


Activated FHHDbf2-H6Mob1TM9 was used to screen the peptide library with the sequence X-X-X-X-R-X-X-S-X-X-X-X. Relative selectivities for amino acids are indicated in parentheses. Bold letters indicate amino acids that are strongly selected; X indicates no selectivity. The one-letter amino acid code is used.

Mah et al. BMC Biochemistry 2005 6:22   doi:10.1186/1471-2091-6-22

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