Figure 2.

Analysis of accordance of two multisequence alignments. The comparison of columns of two multisequence alignments of 15 sequences using the numbering method and T-Coffee revealed five types of column similarity. 48% of the investigated columns were identical in both alignments, 25% of the columns were “highly similar” (up to 3 mismatches out of 15 sequences), 5% were “similar” (4 – 8 mismatches), 12% of the columns had 9 to 12 mismatches and are therefore called “dissimilar” and 10% of the columns showed more than 12 mismatches (“divergent”).

Vogel et al. BMC Biochemistry 2012 13:24   doi:10.1186/1471-2091-13-24
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