Table 2

Biochemicals in the amino acid and peptide pathways
PATHWAY SUB PATHWAY BIOCHEMICAL NAME KEGG
    CPT1c KO
CPT1c WT
Welch's Two-Samplet-Test CAS PUBCHEM
Amino acid Glycine, serine and threonine metabolism glycine C00037 0.91 0.1984 56-40-6; 5,257,127,750
serine C00065 0.98 0.6400 56-45-1; 59,516,857,581
N-acetylserine 1.16 0.2513 97-14-3; 65249
homoserine C00263,C02926 1.04 0.5460 672-15-1; 126,476,971,022
3-phosphoserine C01005 1.06 0.4516 407-41-0;
threonine C00188 0.98 0.8340 72-19-5; 69,710,196,288
allo-threonine C05519 0.98 0.7264 28954-12-3; 992,896,995,276
betaine C00719 0.62 0.0393 107-43-7; 247
Alanine and aspartate metabolism alanine C00041 0.99 0.8540 56-41-7; 59,507,311,724
beta-alanine C00099 0.95 0.7707 56-41-7;107-95-9; 2,394,755,801
N-acetylalanine C02847 0.96 0.7172 97-69-8; 88064
aspartate C00049 1.02 0.5759 56-84-8; 5960
N-acetylaspartate (NAA) C01042 0.98 0.7849 997-55-7;997-55-7; 65065
Glutamate metabolism glutamate C00025 1.10 0.1218 56-86-0; 611
glutamine C00064 0.96 0.3866 56-85-9; 69,920,865,961
gamma-aminobutyrate (GABA) C00334 1.07 0.4581 56-12-2; 6,992,099,119
N-acetylglutamate C00624 1.21 0.1108 5817-08-3; 1549099
N-acetyl-aspartyl-glutamate (NAAG) C12270 1.04 0.6033 3106-85-2; 5255
N-acetylglutamine C02716 0.79 0.1871 2490-97-3; 182230
Histidine metabolism histidine C00135 1.11 0.1815 5934-29-2; 7,733,651,426
Lysine metabolism lysine C00047 0.81 0.0655 56-87-1; 5962
2-aminoadipate C00956 0.99 0.9856 542-32-5;1118-90-7; 469
pipecolate C00408 0.91 0.4383 4043-87-2; 849
glutaroyl carnitine 0.77 0.0244 102636-82-8;
Phenylalanine & tyrosine metabolism phenylalanine C00079 0.93 0.0731 63-91-2; 69,256,656,140
tyrosine C00082 1.10 0.1569 60-18-4; 60,576,942,100
3-(4-hydroxyphenyl)lactate C03672 1.28 0.1580 6482-98-0; 9378
Tryptophan metabolism tryptophan C00078 1.10 0.1009 73-22-3; 69,235,166,305
C-glycosyltryptophan* 1.00 0.9578
5-hydroxyindoleacetate C05635 0.99 0.9982 54-16-0; 1826
Valine, leucine and isoleucine metabolism isoleucine C00407 0.99 0.7705 73-32-5; 791
leucine C00123 0.92 0.1061 61-90-5; 70,457,986,106
valine C00183 1.00 0.9896 72-18-4; 69,710,186,287
alpha-hydroxyisovalerate 0.92 0.9081 600-37-3; 99823
2-methylbutyroylcarnitine 0.98 0.7985 31023-25-3; 6426901
isovalerylcarnitine 0.90 0.1479 6426851
hydroxyisovaleroyl carnitine 0.90 0.0807 99159-87-2;
Cysteine, methionine, SAM, taurine metabolism cysteine C00097 1.13 0.0835 52-90-4;56-89-3; 58,626,419,722
cystine C00491 0.86 0.5529 56-89-3; 595
taurine C00245 1.03 0.7783 107-35-7; 11,234,068,592
S-adenosylhomocysteine (SAH) C00021 0.96 0.4778 979-92-0;
methionine C00073 0.95 0.1654 63-68-3; 69,920,876,137
N-acetylmethionine C02712 0.88 0.1362 65-82-7; 448580
2-hydroxybutyrate (AHB) C05984 1.23 0.5077 3347-90-8; 440864
Urea cycle; arginine-, proline-, metabolism arginine C00062 0.95 0.0964 1119-34-2; 5,246,487,232
ornithine C00077 0.90 0.2453 3184-13-2; 6262
urea C00086 0.71 0.2913 57-13-6; 117,616,150,869
proline C00148 0.97 0.6099 147-85-3; 1,457,426,971,047
N-acetylornithine C00437 1.26 0.3497 6205-08-9; 6,992,102,439,232
trans-4-hydroxyproline C01157 1.03 0.6431 51-35-4; 58,106,971,053
argininosuccinate C03406 0.86 0.3803 156637-58-0; 828
Creatine metabolism creatine C00300 1.03 0.2564 57-00-1; 586
creatinine C00791 1.20 0.1694 60-27-5; 588
Butanoate metabolism 2-aminobutyrate C02261 1.03 0.8503 1492-24-6; 4,396,916,971,251
Polyamine metabolism 5-methylthioadenosine (MTA) C00170 1.08 0.2023 2457-80-9; 439176
putrescine C00134 0.83 0.4688 110-60-1;
spermidine C00315 1.04 0.6645 124-20-9; 1102
spermine C00750 0.99 0.4470 71-44-3; 1103
Guanidino and acetamido metabolism 4-guanidinobutanoate C01035 0.98 0.7911 463-003;463-00-3; 500
Glutathione metabolism glutathione, reduced (GSH) C00051 1.53 0.1024 70-18-8; 124886
5-oxoproline C01879 0.86 0.0291 98-79-3; 7405
glutathione, oxidized (GSSG) C00127 2.15 0.0307 103239-24-3; 6,535,911,215,652
cysteine-glutathione disulfide 1.33 0.0802 13081-14-6; 4247235
Peptide Dipeptide derivative carnosine C00386 0.98 0.8057 305-84-0; 4,392,246,992,100
homocarnosine C00884 1.00 0.9807 3650-73-5; 10243361
gamma-glutamyl gamma-glutamylleucine 0.91 0.1529 2566-39-4; 151023
gamma-glutamylglutamate 1.24 0.1880 1116-22-9; 92865
gamma-glutamylglutamine 0.93 0.4450 10148-81-9; 150914
gamma-glutamylphenylalanine 0.93 0.5544 7432-24-8; 111299

Lee and Wolfgang

Lee and Wolfgang BMC Biochemistry 2012 13:23   doi:10.1186/1471-2091-13-23

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