Table 2 |
|||
| Inhibition assay of pneumococcal sialidases | |||
| Ki(μM) | |||
| Neu5Ac2en | Oseltamivir carboxylate | Zanamivir | |
| NanA | 1.6 | 1.77 | 720 |
| NanB | 330 | -* | -* |
| NanC | 2,010 | -* | -* |
*-, no inhibition observed with inhibitor concentrations up to 7,500 μM.
Hayre et al. BMC Biochemistry 2012 13:19 doi:10.1186/1471-2091-13-19
