Figure 1.

Analysis of the binding specificity of Chromo domains on Celluspots peptide arrays. A) Binding analysis of HP1ß. The upper part of each array analysis shows the image of the array. Peptide spots are annotated on the left copy of the duplicates. The color code is described on the right side of the image. The red arrows indicate unbound peptide spots carrying the target modifications and secondary inhibiting modifications, which are specified on the right side of the image. In the lower part of the figure, a scatter plot of the binding intensities to corresponding peptides on both identical copies of the array and a bar diagram indicating the range of deviations is shown. B) Binding analysis of the MPP8 Chromo domain. For a description of the figure see legend of panel A.