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Resolution: standard / high Figure 6.
Illustration of the wide range of relative percent abundances of Native and S-Cysteinylated
albumin found in the human population. Data were acquired from human plasma obtained from A) an individual with congestive
heart failure, diabetes, and a history of myocardial infarction (4.5% Native form),
and B) a healthy individual (66% Native form). Deconvoluted "MH+" peaks are assigned as follows: 66254 = N-terminal truncation (-DA) (Calc. 66253),
66325 = N-terminal truncation (-D) (Calc. 66324), 66440 = Native/unmodified (Calc.
66439), 66538 = Non-covalent phosphate adduct (plasma anticoagulant artifact) (Calc.
66537), 66559 = S-Cysteinylated (Calc. 66558), 66602 = Glycated native form (Calc.
66601), 66721 = Glycated S-Cysteinylated form (Calc. 66720).
Rehder and Borges BMC Biochemistry 2010 11:25 doi:10.1186/1471-2091-11-25 |