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Spotlight on… Metabolism


New Content ItemThe importance of metabolism beyond energy production and macromolecule synthesis has become evident in recent years. Increasingly, we appreciate the importance of metabolites and metabolic fluxes in cell signalling, post-translational modifications and cell survival, with implications for a range of diseases from cancer to diabetes and natural aging. Here we highlight some recent research from across the BMC Series that investigates the evolution, adaptation and regulation of metabolism.

Metabolic Adaptation and Evolution

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Genome-centric metagenomics reveals insights into the evolution and metabolism of a new free-living group in Rhizobiales

Leandro Nascimento Lemos, Fabíola Marques de Carvalho, Alexandra Gerber, Ana Paula C. Guimarães, Celio Roberto Jonck, Luciane Prioli Ciapina & Ana Tereza Ribeiro de Vasconcelos

BMC Microbiology volume 21, Article number: 294 (2021) 

Cross-species transcriptomes reveal species-specific and shared molecular adaptations for plants development on iron-rich rocky outcrops soils

Mariana Costa Dias, Cecílio Caldeira, Markus Gastauer, Silvio Ramos & Guilherme Oliveira

BMC Genomics volume 23, Article number: 313 (2022)

Genetic mapping of metabolic traits in the blind Mexican cavefish reveals sex-dependent quantitative trait loci associated with cave adaptation

Misty R. Riddle, Ariel Aspiras, Fleur Damen, Suzanne McGaugh, Julius A. Tabin & Clifford J. Tabin

BMC Ecology and Evolution volume 21, Article number: 94 (2021)

Genome-scale insights into the metabolic versatility of Limosilactobacillus reuteri

Hao Luo, Peishun Li, Hao Wang, Stefan Roos, Boyang Ji & Jens Nielsen

BMC Biotechnology volume 21, Article number: 46 (2021) 

Investigating the Metabolome

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MetHoS: a platform for large-scale processing, storage and analysis of metabolomics data

Konstantinos Tzanakis, Tim W. Nattkemper, Karsten Niehaus & Stefan P. Albaum

BMC Bioinformatics volume 23, Article number: 267 (2022)

Large dependency of intracellular NAD and CoA pools on cultivation conditions in Saccharomyces cerevisiae

Kanhaiya Kumar & Per Bruheim

BMC Research Notes volume 14, Article number: 372 (2021) 

Transcriptional regulation of metabolism

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Comparative transcriptome and metabolome analysis reveal glutathione metabolic network and functional genes underlying blue and red-light mediation in maize seedling leaf

Tiedong Liu & Xiwen Zhang 

BMC Plant Biology volume 21, Article number: 593 (2021)

Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Neeraj Sinha, Evert M. van Schothorst, Guido J. E. J. Hooiveld, Jaap Keijer, Vitor A. P. Martins dos Santos & Maria Suarez-Diez 

BMC Bioinformatics volume 22, Article number: 574 (2021)

Intermittent fasting induces chronic changes in the hepatic gene expression of Red Jungle Fowl (Gallus gallus)

Caroline Lindholm, Petros Batakis, Jordi Altimiras & John Lees 

BMC Genomics volume 23, Article number: 304 (2022)