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BMC Series Focus Issue

Infection and health

New Content ItemWith the ongoing Covid-19 pandemic, the importance of understanding infection, its biology, risk factors, spread, diagnosis, and treatment has come into the limelight. While research on SARS-CoV2 and Covid-19 has taken the spotlight, research on other infections have also been boosted with common trends and combating strategies surfacing. This month, the BMC Series journals would like to dedicate their focus issue to the recent research into infections and health highlighting four key topics within research on infection - the biology, recent advances in detection and diagnosis, the risk factors and incidence reports and finally on the advances in treatment and combating of infection.  Read the articles in the focus issue from across the BMC Series journals, below.

New Content ItemBy sharing this research, we wish to support the UN's Sustainable Development Goals, and highlight content that could make a difference to solving global problems.

JAK-inhibitor and type I interferon ability to produce favorable clinical outcomes in COVID-19 patients: a systematic review and meta-analysis
Lucas Walz, Avi J. Cohen, Andre P. Rebaza, James Vanchieri, Martin D. Slade, Charles S. Dela Cruz & Lokesh Sharma
BMC Infectious Diseases volume 21, Article number: 47 (2021)

Identification of virulence associated milRNAs and their bidirectional targets in Rhizoctonia solani and maize during infection
Hongxu Meng, Shaoli Wang, Wei Yang, Xinhua Ding, Ning Li, Zhaohui Chu & Xiaoming Li
BMC Plant Biology volume 21, Article number: 155 (2021)

Time-course transcriptome analysis of host cell response to poxvirus infection using a dual long-read sequencing approach
Zoltán Maróti, Dóra Tombácz, István Prazsák, Norbert Moldován, Zsolt Csabai, Gábor Torma, Zsolt Balázs, Tibor Kalmár, Béla Dénes, Michael Snyder & Zsolt Boldogkői
BMC Research Notes volume 14, Article number: 239 (2021)

Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis
Irina Vlasova-St Louis, Abdu K. Musubire, David B. Meya, Henry W. Nabeta, Hesham Mohei, David R. Boulware & Paul R. Bohjanen
BMC Medical Genomics volume 14, Article number: 108 (2021)

Human microbiota modulation via QseC sensor kinase mediated in the Escherichia coli O104:H4 outbreak strain infection in microbiome model
Tamara Renata Machado Ribeiro, Mateus Kawata Salgaço, Maria Angela Tallarico Adorno, Miriam Aparecida da Silva, Roxane Maria Fontes Piazza, Katia Sivieri & Cristiano Gallina Moreira
BMC Microbiology volume 21, Article number: 163 (2021)

Blood transcriptome analysis of patients with uncomplicated bacterial infection and sepsis
Data Note
Velma Herwanto, Benjamin Tang, Ya Wang, Maryam Shojaei, Marek Nalos, Amith Shetty, Kevin Lai, Anthony S. McLean & Klaus Schughart
BMC Research Notes volume 14, Article number: 76 (2021)

Effect of epigallocatechin gallate on dental biofilm of Streptococcus mutans: An in vitro study
Mor Schneider-Rayman, Doron Steinberg, Ronit Vogt Sionov, Michael Friedman & Miriam Shalish
BMC Oral Health volume 21, Article number: 447 (2021)

Hypergraph models of biological networks to identify genes critical to pathogenic viral response
Song Feng, Emily Heath, Brett Jefferson, Cliff Joslyn, Henry Kvinge, Hugh D. Mitchell, Brenda Praggastis, Amie J. Eisfeld, Amy C. Sims, Larissa B. Thackray, Shufang Fan, Kevin B. Walters, Peter J. Halfmann, Danielle Westhoff-Smith, Qing Tan, Vineet D. Menachery, Timothy P. Sheahan, Adam S. Cockrell, Jacob F. Kocher, Kelly G. Stratton, Natalie C. Heller, Lisa M. Bramer, Michael S. Diamond, Ralph S. Baric, Katrina M. Waters, Yoshihiro Kawaoka, Jason E. McDermott & Emilie Purvine -Show fewer authors
BMC Bioinformatics volume 22, Article number: 287 (2021)

The diagnostic value of metagenomic next⁃generation sequencing in infectious diseases
Hongxia Duan, Xuan Li, Aihong Mei, Ping Li, Yang Liu, Xiaofeng Li, Weiwei Li, Changhui Wang & Shuanshuan Xie
BMC Infectious Diseases volume 21, Article number: 62 (2021)

Detection of SARS-CoV-2 in fecal samples with different pretreatment methods and PCR kits
Ranran Cao, Lirong Bao, Ming Pan, Cheng Zhang, Hongyu Liao, Li Liu, Yan Li & Mingyuan Li
BMC Microbiology volume 21, Article number: 56 (2021)

Manual Annotation Studio (MAS): a collaborative platform for manual functional annotation of viral and microbial genomes
Matthew R. Lueder, Regina Z. Cer, Miles Patrick, Logan J. Voegtly, Kyle A. Long, Gregory K. Rice & Kimberly A. Bishop-Lilly
BMC Genomics volume 22, Article number: 733 (2021)

Development and comparison of cross-linking and non-crosslinking probe-gold nanoparticle hybridization assays for direct detection of unamplified bovine viral diarrhea virus-RNA
Zahra Heidari, Seyedeh Elham Rezatofighi & Saadat Rastegarzadeh
BMC Biotechnology volume 21, Article number: 30 (2021)

Clinical significance of D-dimer levels in refractory Mycoplasma pneumoniae pneumonia
Xia Huang, Dan Li, Feng Liu, Deyu Zhao, Yifan Zhu & Heng Tang
BMC Infectious Diseases volume 21, Article number: 14 (2021)

Globulin, the albumin-to-globulin ratio, and fibrinogen perform well in the diagnosis of Periprosthetic joint infection
Huhu Wang, Haikang Zhou, Rendong Jiang, Zhenhao Qian, Fei Wang & Li Cao
BMC Musculoskeletal Disorders volume 22, Article number: 583 (2021)

Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection
Data Note
Rajendra KC & Ronan F. O’Toole
BMC Research Notes volume 14, Article number: 123 (2021)

Serial interval and incubation period of COVID-19: a systematic review and meta-analysis
Muluneh Alene, Leltework Yismaw, Moges Agazhe Assemie, Daniel Bekele Ketema, Wodaje Gietaneh & Tilahun Yemanu Birhan
BMC Infectious Diseases volume 21, Article number: 257 (2021)

Hepatitis E Virus and rheumatic diseases: what do rheumatologists need to know?
Salvatore Di Bartolomeo, Francesco Carubbi & Paola Cipriani
BMC Rheumatology volume 4, Article number: 51 (2020)

Incidence, severity and perceived susceptibility of COVID-19 in the UK CrossFit population
Athalie Redwood-Brown, Grant William Ralston & Jennifer Wilson
BMC Sports Science, Medicine and Rehabilitation volume 13, Article number: 106 (2021)

Microbiological findings in early and late implant loss: an observational clinical case-controlled study
Michael Korsch, Silke-Mareike Marten, Dominic Stoll, Christopher Prechtl & Andreas Dötsch
BMC Oral Health volume 21, Article number: 112 (2021)

The genetic impact of an Ebola outbreak on a wild gorilla population
Claudia Fontsere, Peter Frandsen, Jessica Hernandez-Rodriguez, Jonas Niemann, Camilla Hjorth Scharff-Olsen, Dominique Vallet, Pascaline Le Gouar, Nelly Ménard, Arcadi Navarro, Hans R. Siegismund, Christina Hvilsom, M. Thomas P. Gilbert, Martin Kuhlwilm, David Hughes & Tomas Marques-Bonet
BMC Genomics volume 22, Article number: 735 (2021)

Intriguing findings of liver fibrosis following COVID-19
Oksana Kolesova, Ieva Vanaga, Sniedze Laivacuma, Aleksejs Derovs, Aleksandrs Kolesovs, Maija Radzina, Ardis Platkajis, Jelena Eglite, Elvira Hagina, Seda Arutjunana, Davis Simanis Putrins, Jelena Storozenko, Baiba Rozentale & Ludmila Viksna
BMC Gastroenterology volume 21, Article number: 370 (2021)

Dietary intake, intestinal infection, and safe drinking water among children with anemia in Peru: a cross-sectional analysis
Christopher M. Westgard, Luis A. Orrego-Ferreyros, Liz Franco Calderón & Alexandra M. Rogers
BMC Nutrition volume 7, Article number: 11 (2021)

Risk factors associated with respiratory infectious disease-related presenteeism: a rapid review
Sarah Daniels, Hua Wei, Yang Han, Heather Catt, David W. Denning, Ian Hall, Martyn Regan, Arpana Verma, Carl A. Whitfield & Martie van Tongeren
BMC Public Health volume 21, Article number: 1955 (2021)

A prospectus of plant growth promoting endophytic bacterium from orchid (Vanda cristata)
Sujit Shah, Krishna Chand, Bhagwan Rekadwad, Yogesh S. Shouche, Jyotsna Sharma & Bijaya Pant
BMC Biotechnology volume 21, Article number: 16 (2021)

Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections
Timothy J. Straub, Wen-Chi Chou, Abigail L. Manson, Henry L. Schreiber IV, Bruce J. Walker, Christopher A. Desjardins, Sinéad B. Chapman, Kerrie L. Kaspar, Orsalem J. Kahsai, Elizabeth Traylor, Karen W. Dodson, Meredith A. J. Hullar, Scott J. Hultgren, Christina Khoo & Ashlee M. Earl
BMC Microbiology volume 21, Article number: 53 (2021)

Tooth mousse containing casein phosphopeptide-amorphous calcium phosphate prevents biofilm formation of Streptococcus mutans
Ronit Vogt Sionov, Danae Tsavdaridou, Muna Aqawi, Batya Zaks, Doron Steinberg & Miriam Shalish
BMC Oral Health volume 21, Article number: 136 (2021)

Lefamulin efficacy and safety in a pooled phase 3 clinical trial population with community-acquired bacterial pneumonia and common clinical comorbidities
Thomas M. File Jr., Elizabeth Alexander, Lisa Goldberg, Anita F. Das, Christian Sandrock, Susanne Paukner & Gregory J. Moran
BMC Pulmonary Medicine volume 21, Article number: 154 (2021)

Uncovering the effects of heterogeneity and parameter sensitivity on within-host dynamics of disease: malaria as a case study
Shade Horn, Jacky L. Snoep & David D. van Niekerk 
BMC Bioinformatics volume 22, Article number: 384 (2021)

Effect of educational intervention on the appropriate use of oral antimicrobials in oral and maxillofacial surgery: a retrospective secondary data analysis
Junya Kusumoto, Atsushi Uda, Takeshi Kimura, Shungo Furudoi, Ryosuke Yoshii, Megumi Matsumura, Takayuki Miyara & Masaya Akashi
BMC Oral Health volume 21, Article number: 20 (2021)

Medical thoracoscopy treatment for pleural infections: a systematic review and meta-analysis
Michele Mondoni, Laura Saderi, Federica Trogu, Silvia Terraneo, Paolo Carlucci, Filippo Ghelma, Stefano Centanni & Giovanni Sotgiu
BMC Pulmonary Medicine volume 21, Article number: 127 (2021)

Overcoming the limitations of locally administered oncolytic virotherapy
JinWoo Hong & Chae-Ok Yun
BMC Biomedical Engineering volume 1, Article number: 17 (2019)

Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review
L. Susan Wieland, Vanessa Piechotta, Termeh Feinberg, Emilie Ludeman, Brian Hutton, Salmaan Kanji, Dugald Seely & Chantelle Garritty
BMC Complementary Medicine and Therapies volume 21, Article number: 112 (2021)