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Reproducibility and research integrity

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Research integrity is an important driver of reliable and trustworthy research, and includes issues such as reproducibility and replicability. There is a need to promote robust research, starting at the lab bench and extending to the dissemination of findings to the scientific community, as well as to the public. 

Following a call from the UK House of Commons Science and Technology Committee for evidence on reproducibility and research integrity, and the roles different institutions play in this, BMC Research Notes has partnered with the UK Reproducibility Network to provide a platform to share feedback on the topic with the wider scientific community. 

In this BMC Research Notes collection, we welcomed contributions on the following topics:

  • Factors that influence reproducibility and research integrity;
  • The role of different stakeholders in addressing these factors;
  • Proposals for improving research integrity and quality;
  • Guidance and support for researchers.

We welcomed articles that are based on submissions to the Science and Technology Committee, including submissions by individuals, groups or organisations. Contributions from across the globe are invited. 

Articles were submitted as Commentaries, which can be presented as thought-provoking opinion pieces or guidance documents. 

All articles underwent the journal’s standard peer-review process and article-processing charges applied (with standard waiver policy). 


  1. Proponents of open science often refer to issues pertaining to research integrity and vice versa. In this commentary, we argue that concepts such as responsible research practices, transparency, and open scien...

    Authors: Tamarinde Haven, Gowri Gopalakrishna, Joeri Tijdink, Dorien van der Schot and Lex Bouter
    Citation: BMC Research Notes 2022 15:302
  2. Increasing the reproducibility and trustworthiness of biomedical research requires engaging stakeholders from all levels in an institutional setting. The QUEST Center for Responsible Research aims to develop a...

    Authors: Natascha Drude, Lorena Martinez-Gamboa, Tamarinde Haven, Constance Holman, Martin Holst, Silke Kniffert, Sarah McCann, Torsten Rackoll, Robert Schulz and Sarah Weschke
    Citation: BMC Research Notes 2022 15:270
  3. Mentors have the responsibility to guide their mentees through academic and scientific challenges that they might encounter during their educational and professional development. In embodying the role of mento...

    Authors: Daniel Pizzolato and Kris Dierickx
    Citation: BMC Research Notes 2022 15:209
  4. The rising rate of preprints and publications, combined with persistent inadequate reporting practices and problems with study design and execution, have strained the traditional peer review system. Automated ...

    Authors: Robert Schulz, Adrian Barnett, René Bernard, Nicholas J. L. Brown, Jennifer A. Byrne, Peter Eckmann, Małgorzata A. Gazda, Halil Kilicoglu, Eric M. Prager, Maia Salholz-Hillel, Gerben ter Riet, Timothy Vines, Colby J. Vorland, Han Zhuang, Anita Bandrowski and Tracey L. Weissgerber
    Citation: BMC Research Notes 2022 15:203
  5. One major source of exhaustion for researchers is the redundant paperwork of three different documents—research papers, ethics review applications, and research grant applications—for the same research plan. T...

    Authors: Yuki Mori, Kaito Takashima, Kohei Ueda, Kyoshiro Sasaki and Yuki Yamada
    Citation: BMC Research Notes 2022 15:184
  6. Poor quality medical research causes serious harms by misleading healthcare professionals and policymakers, decreasing trust in science and medicine, and wasting public funds. Here we outline underlying proble...

    Authors: Stephen H. Bradley, Nicholas J. DeVito, Kelly E. Lloyd, Patricia Logullo and Jessica E. Butler
    Citation: BMC Research Notes 2022 15:165
  7. Journal peer review regulates the flow of ideas through an academic discipline and thus has the power to shape what a research community knows, actively investigates, and recommends to policymakers and the wid...

    Authors: Alexandru Marcoci, Ans Vercammen, Martin Bush, Daniel G. Hamilton, Anca Hanea, Victoria Hemming, Bonnie C. Wintle, Mark Burgman and Fiona Fidler
    Citation: BMC Research Notes 2022 15:127
  8. Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. How...

    Authors: Olivia S. Kowalczyk, Alexandra Lautarescu, Elisabet Blok, Lorenza Dall’Aglio and Samuel J. Westwood
    Citation: BMC Research Notes 2022 15:116
  9. Open science and open data within scholarly research programs are growing both in popularity and by requirement from grant funding agencies and journal publishers. A central component of open data management, ...

    Authors: Andrew Wright Child, Jennifer Hinds, Lucas Sheneman and Sven Buerki
    Citation: BMC Research Notes 2022 15:106
  10. The UK House of Commons Science and Technology Committee has called for evidence on the roles that different stakeholders play in reproducibility and research integrity. Of central priority are proposals for i...

    Authors: Flávio Azevedo, Meng Liu, Charlotte R. Pennington, Madeleine Pownall, Thomas Rhys Evans, Sam Parsons, Mahmoud Medhat Elsherif, Leticia Micheli and Samuel J. Westwood
    Citation: BMC Research Notes 2022 15:75
  11. Many disciplines are facing a “reproducibility crisis”, which has precipitated much discussion about how to improve research integrity, reproducibility, and transparency. A unified effort across all sectors, l...

    Authors: Suzanne L. K. Stewart, Charlotte R. Pennington, Gonçalo R. da Silva, Nick Ballou, Jessica Butler, Zoltan Dienes, Caroline Jay, Stephanie Rossit and Anna Samara
    Citation: BMC Research Notes 2022 15:58
  12. Various factors contribute to low reproducibility and replicability of scientific findings. Whilst not all of these are necessarily problematic, there is growing acceptance that there is room for improvement. ...

    Authors: Emma Ganley, Anne-Marie Coriat, Sarah Shenow and David Prosser
    Citation: BMC Research Notes 2022 15:51
  13. There are many factors that contribute to the reproducibility and replicability of scientific research. There is a need to understand the research ecosystem, and improvements will require combined efforts acro...

    Authors: Marcus R. Munafò, Chris Chambers, Alexandra Collins, Laura Fortunato and Malcolm Macleod
    Citation: BMC Research Notes 2022 15:43
  14. The adoption and incentivisation of open and transparent research practices is critical in addressing issues around research reproducibility and research integrity. These practices will require training and fu...

    Authors: Andrew J. Stewart, Emily K. Farran, James A. Grange, Malcolm Macleod, Marcus Munafò, Phil Newton and David R. Shanks
    Citation: BMC Research Notes 2021 14:458

Blogs
Reproducibility and Research Integrity – a call for content
By Prof. Marcus Munafò
BMC Series blog network, 25 Aug 2021

More BMC blogs about reproducibility and research integrity.

Further reading
Reproducibility and research integrity: Inquiry
UK Parliament, Science and Technology Committee
Launched 23 July 2021

1,500 scientists lift the lid on reproducibility
By Monya Baker
Nature 533, 452–454 (2016)

Resources
Open Research at Springer Nature
Research Data at Springer Nature
BMC editorial policies