Mobile DNA elements threaten genome integrity but are countered by host defenses, with the resulting arms race producing a genomic landscape that is dominated by transposable elements (TEs) and their relics. Epigenetic processes are involved in both defending against these invaders and maintaining gene expression despite the onslaught, with occasional domestication resulting in novel regulatory elements. Recent progress in genomic and epigenetic technologies have led to a deeper but as-yet incomplete understanding of these processes and their impacts on the genome and epigenome.
With this collection, Epigenetics & Chromatin is aiming to bring together primary research, methodological advances and critical reviews on all aspects of mobile element epigenetics. Examples include, but are not limited to, epigenetic processes such as DNA methylation, histone modification and chromatin dynamics affecting TEs and outcomes such as silencing of repeats but also acquisition and activities of domesticated elements in gene regulation.