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76.

21579
Accesses

Review   Open Access Highly Accessed

Beta-thalassemia

Renzo Galanello, Raffaella Origa Orphanet Journal of Rare Diseases 2010, 5:11 (21 May 2010)

Abstract | Full text | PDF | PubMed

77.

21391
Accesses

Review   Open Access Highly Accessed

Critical care management of severe traumatic brain injury in adults

Samir H Haddad, Yaseen M Arabi Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:12 (3 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

21018
Accesses

Research   Open Access Highly Accessed

Modeling gene expression using chromatin features in various cellular contexts

Xianjun Dong, Melissa C Greven, Anshul Kundaje, Sarah Djebali, James B Brown, Chao Cheng, Thomas R Gingeras, Mark Gerstein, Roderic Guigó, Ewan Birney, Zhiping Weng Genome Biology 2012, 13:R53 (5 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Models for linking gene expression with chromatin features vary according to cellular context and RNA measurement method

79.

21004
Accesses

Review   Open Access Highly Accessed

International Society of Sports Nutrition position stand: energy drinks

Bill Campbell, Colin Wilborn, Paul La Bounty, Lem Taylor, Mike T Nelson, Mike Greenwood, Tim N Ziegenfuss, Hector L Lopez, Jay R Hoffman, Jeffrey R Stout, Stephen Schmitz, Rick Collins, Doug S Kalman, Jose Antonio, Richard B Kreider Journal of the International Society of Sports Nutrition 2013, 10:1 (3 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A systematic review on energy drinks, from the International Society of Sports Nutrition.

80.

20962
Accesses

Research article   Open Access Highly Accessed

Extremely short duration high intensity interval training substantially improves insulin action in young healthy males

John A Babraj, Niels BJ Vollaard, Cameron Keast, Fergus M Guppy, Greg Cottrell, James A Timmons BMC Endocrine Disorders 2009, 9:3 (28 January 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Low-volume, high-intensity exercise improves insulin action in sedentary males and may prove to be an efficient way of reducing risk factors for metabolic disease in those with little time for conventional high volume regimes.

81.

20805
Accesses

Research   Open Access Highly Accessed

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

Jagadeesh K Venkatesan, Myriam Ekici, Henning Madry, Gertrud Schmitt, Dieter Kohn, Magali Cucchiarini Stem Cell Research & Therapy 2012, 3:22 (28 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Transfer of SOX9 via replication-defective recombinant adeno-associated virus (rAAV) vector enhances the chondrogenic potential of human mesenchymal stem cells, with potential for future therapeutic applications to restore articular cartilage defects.

82.

20774
Accesses

Correspondence   Open Access Highly Accessed

Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics

Barry R Zeeberg, Joseph Riss, David W Kane, Kimberly J Bussey, Edward Uchio, W Marston Linehan, J Carl Barrett, John N Weinstein BMC Bioinformatics 2004, 5:80 (23 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 7 comments

83.

20754
Accesses

Hypothesis   Open Access Highly Accessed

Musical beauty and information compression: Complex to the ear but simple to the mind?

Nicholas J Hudson BMC Research Notes 2011, 4:9 (20 January 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Despite their apparent complexity, many musical masterpieces can be reduced to simple patterns by the brain, and this "compressibility" may play a role in the pleasure we have listening to them, a hypothesis suggests.

84.

20392
Accesses

Research article   Open Access Highly Accessed

Cross-national epidemiology of DSM-IV major depressive episode

Evelyn Bromet, Laura Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Mora, Mark Browne, Jose Posada-Villa, Maria Viana, David R Williams, Ronald C Kessler BMC Medicine 2011, 9:90 (26 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Major depression is a significant public health problem around the globe which affects women twice as commonly as men and is most strongly correlated with being separated, divorced or widowed.

85.

20273
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Review   Open Access Highly Accessed

Creatine supplementation with specific view to exercise/sports performance: an update

Robert Cooper, Fernando Naclerio, Judith Allgrove, Alfonso Jimenez Journal of the International Society of Sports Nutrition 2012, 9:33 (20 July 2012)

Abstract | Full text | PDF | PubMed

86.

20062
Accesses

Research article   Open Access Highly Accessed

The purple line as a measure of labour progress: a longitudinal study

Ashley Shepherd, Helen Cheyne, Susan Kennedy, Colette McIntosh, Maggie Styles, Catherine Niven BMC Pregnancy and Childbirth 2010, 10:54 (16 September 2010)

Abstract | Full text | PDF | PubMed

87.

19926
Accesses

Case Report   Open Access Highly Accessed

Overabundant milk supply: an alternative way to intervene by full drainage and block feeding

Caroline GA van Veldhuizen-Staas International Breastfeeding Journal 2007, 2:11 (29 August 2007)

Abstract | Full text | PDF | PubMed | 1 comment

88.

19772
Accesses

Review   Free

Weaning from mechanical ventilation

Inmaculada Alía, Andrés Esteban Critical Care 2000, 4:72-80 (18 February 2000)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

89.

19613
Accesses

Review   Open Access Highly Accessed

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

Rainer J Klement, Ulrike Kämmerer Nutrition & Metabolism 2011, 8:75 (26 October 2011)

Abstract | Full text | PDF | PubMed

90.

19558
Accesses

Research   Open Access Highly Accessed

Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations

Cynthia M Kroeger, Monica C Klempel, Surabhi Bhutani, John F Trepanowski, Christine C Tangney, Krista A Varady Nutrition & Metabolism 2012, 9:98 (31 October 2012)

Abstract | Full text | PDF | PubMed

91.

19537
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Review   Open Access Highly Accessed

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Gerhard J Molderings, Stefan Brettner, Jürgen Homann, Lawrence B Afrin Journal of Hematology & Oncology 2011, 4:10 (22 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

92.

19411
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Herpes simplex virus infection in pregnancy and in neonate: status of art of epidemiology, diagnosis, therapy and prevention

Elena Anzivino, Daniela Fioriti, Monica Mischitelli, Anna Bellizzi, Valentina Barucca, Fernanda Chiarini, Valeria Pietropaolo Virology Journal 2009, 6:40 (6 April 2009)

Abstract | Full text | PDF | PubMed

93.

19350
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Review   Open Access Highly Accessed

The Bhopal disaster and its aftermath: a review

Edward Broughton Environmental Health: A Global Access Science Source 2005, 4:6 (10 May 2005)

Abstract | Full text | PDF | PubMed

94.

19268
Accesses

Brief communication   Open Access Highly Accessed

Daytime pattern of post-exercise protein intake affects whole-body protein turnover in resistance-trained males

Daniel R Moore, Jose Areta, Vernon G Coffey, Trent Stellingwerff, Stuart M Phillips, Louise M Burke, Marilyn Cléroux, Jean-Philippe Godin, John A Hawley Nutrition & Metabolism 2012, 9:91 (16 October 2012)

Abstract | Full text | PDF | PubMed

95.

19217
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Research   Open Access Highly Accessed

Motivation and job satisfaction among medical and nursing staff in a Cyprus public general hospital

Persefoni Lambrou, Nick Kontodimopoulos, Dimitris Niakas Human Resources for Health 2010, 8:26 (16 November 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

96.

19174
Accesses

Commentary   Open Access Highly Accessed

A reflection on HIV/AIDS research after 25 years

Robert C Gallo Retrovirology 2006, 3:72 (20 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

97.

19152
Accesses

Research   Open Access Highly Accessed

IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation

Judith L Ngondi, Blanche C Etoundi, Christine B Nyangono, Carl MF Mbofung, Julius E Oben Lipids in Health and Disease 2009, 8:7 (2 March 2009)

Abstract | Full text | PDF | PubMed

98.

19065
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Comment   Subscription Highly Accessed

A 10-step guide to party conversation for bioinformaticians

Alicia Oshlack Genome Biology 2013, 14:104 (29 January 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Alicia Oshlack's 10-step guide to party conversation for bioinformaticians

99.

18999
Accesses

Method   Open Access Highly Accessed

A scaling normalization method for differential expression analysis of RNA-seq data

Mark D Robinson, Alicia Oshlack Genome Biology 2010, 11:R25 (2 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A novel and empirical method for normalization of RNA-seq data is presented

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